Motor unit remodelling in multifocal motor neuropathy: The importance of axonal loss
نویسندگان
چکیده
منابع مشابه
Multifocal motor neuropathy.
We report the case of a patient with multifocal motor neuropathy. Electrophysiological studies showed typical multifocal conduction blocks, but the search for anti-GM1 antibodies was negative. This case provide the heterogeneity of this clinical entity.
متن کاملDemyelination and axonal loss in multifocal motor neuropathy: distribution and relation to weakness.
Multifocal motor neuropathy (MMN) is characterized by a slowly progressive, asymmetric weakness of the limbs without sensory loss. The arms are usually affected to a greater extent than the legs, and distal muscles more than proximal muscles. The distribution of electrophysiological abnormalities and its correlation with weak muscle groups in MMN have not been investigated systematically. The a...
متن کاملAcute motor axonal neuropathy
By Sameera Salman Ghauri (Dr. Ghauri of University of Texas Houston Health Science Center has no relevant financial relationships to disclose.) Suur Biliciler MD (Dr. Biliciler of University of Texas Houston Health Science Center has no relevant financial relationships to disclose.) Thy Nguyen MD (Dr. Nguyen of University of Texas Health Science Center has no relevant financial relationships to...
متن کاملPathophysiology of multifocal motor neuropathy
Multifocal motor neuropathy is a unique disease that not only challenges the electromyographer to make differential diagnosis from a fatal disease but also provides an opportunity to reconsider the mechanism of conduction block in demyelinating neuropathies. Conduction block or slowing is not always a consequence of demyelination, but can be due to membrane hyperpolarisation or depolarisation, ...
متن کاملDistinctive abnormalities of motor axonal strength-duration properties in multifocal motor neuropathy and in motor neurone disease.
The strength-duration function is a classic measure of neural excitability. When studied on peripheral motor axons it reflects the intrinsic nodal membrane properties, and its time-constant (tau(SD) or chronaxie) predominantly depends on non-voltage-gated, rest Na(+) inward conductances. We assessed the strength-duration curve of ulnar motor axons in 22 nerves of healthy controls, in 18 nerves ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Neurophysiology
سال: 2017
ISSN: 1388-2457
DOI: 10.1016/j.clinph.2017.07.414